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|A very significant One Health Alliance: Clinical Translational Science Award One Health Alliance (COHA) - Thursday, January 11, 2018
A very significant One Health Alliance https://ctsaonehealthalliance.org/
Clinical Translational Science Award One Health Alliance (COHA)
Advancing the understanding of diseases shared by humans and animals
One Health is the integrative effort of multiple disciplines working together locally, nationally, and globally to attain optimal health for people, animals, and the shared environment.
The Clinical and Translational Science Award One Health Alliance (COHA) is comprised of veterinary schools partnered with medical and other colleagues through a National Institutes of Health Clinical Translational Science Award (CTSA). COHA’s mission is to advance our understanding of diseases shared by humans and animals. The alliance leverages the expertise of physicians, research scientists, veterinarians, and other professionals to find solutions for medical problems and to address the well-being of humans, animals, and the environment. This approach will capitalize on One Health opportunities that accelerate translational research.
Our Member Institutions
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|Gold Headed Cane Awarded to One Health Initiative Team Member – Dr. Lisa A. Conti - Monday, July 31, 2017
Dr. Craig N. Carter, left presenting American Veterinary Epidemiology Society (AVES) Gold Headed Cane to Dr. Lisa A. Conti, right.
2017 Gold Headed Cane Awarded to One Health Initiative Team Member – Dr. Lisa A. Conti
Dr. Lisa A. Conti received the prestigious American Veterinary Epidemiology Society (AVES) KF Meyer/James H. Steele Gold Headed Cane Award from Dr. Craig N. Carter, current AVES President at the American Veterinary Medical Association convention in Indianapolis, Indiana (USA) on July 24, 2017.
“The award was in recognition of Dr. Conti’s devotion to and achievements in the advancement of animal health, human health and One Health” said Dr. Carter. He went on to say, “... you are so very deserving.”
Dr. Conti https://goo.gl/49F5rz is currently the Deputy Commissioner and Chief Science Officer of the Florida Department of Agriculture and Consumer Services, overseeing the divisions of Food Safety, Agriculture Environmental Services, Aquaculture, Animal Industry, and Plant Industry. Prior appointments were with the Florida Department of Health for 23 years, as Division Director of Environmental Health, Florida State Public Health Veterinarian and State HIV/AIDS Surveillance Coordinator. She has authored or co-authored numerous journal articles on One Health, public health, HIV/AIDS surveillance, vector-borne and zoonotic disease topics. She is Coeditor with prominent One Health physician Dr. Peter Rabinowitz, of the book Human-Animal Medicine: Clinical Approaches to Zoonoses, Toxicants and Other Shared Health Risks https://www.amazon.com/Human-Animal-Medicine-Clinical-Approaches-Toxicants/dp/1416068376 and Co-editor of Confronting Emerging Zoonoses: The One Health Paradigm http://www.springer.com/978-4-431-55119-5.
Dr. Conti serves on the NIH National Advisory Environmental Health Sciences Council. She is a member of the One Health Initiative pro bono team currently comprised of two physicians and two veterinarians. She was a founding member and Chair of the State Environmental Health Directors with the Association of State and Territorial Health Officers. She was a founding member of the Florida Rabies Control and Prevention Advisory Committee, sat on the Rabies Compendium Committee of the National Association of State Public Health Veterinarians, was an Executive Board member of the Florida Veterinary Medical Association (FVMA) and established and chaired the FVMA One Health Committee from 1995-2013. Dr. Conti served on the American Veterinary Medical Association (AVMA) Council on Public Relations representing Public Health.
She was an Affiliate with the Yale University School of Medicine on Human-Animal Medicine projects; an Adjunct Professor at Florida State University having taught Food Safety and Epidemiology courses; Courtesy Associate Professor at the University of Florida, College of Veterinary Medicine’s Department of Infectious Diseases and Pathology; and, has taught Anatomy and Physiology at Tallahassee Community College.
She earned her Doctor of Veterinary Medical degree from the University of Florida, Master of Public Health (Public Health Administration) from the University of South Florida and Bachelor of Science (Chemistry/Math) from the University of Miami. She is a Certified Public Manager through Florida State University, and Board Certified in Preventive Medicine through the American College of Veterinary Preventive Medicine.
Dr. Conti is a recipient of the Florida Public Health Woman of the Year Award and the AVMA Public Service Award.
Dr. Terry McElwain was also awarded the KF Meyer/James H. Steele Gold Headed Cane for outstanding leadership and career contributions in epidemiology, public health and One Health. Dr. McElwain earned his DVM from Kansas State University. After a short stint in clinical practice in Pennsylvania, he completed a residency in pathology and a PhD in Veterinary Pathology and Microbiology at Washington State University. He is a Diplomate of the American College of Veterinary Pathologists. After serving as an assistant professor of pathology, infectious diseases, and immunology at the University of Florida and Washington State University, he became the Director and Executive Director, of the Washington Animal Disease Diagnostic Laboratory in 1993, and Director of the Animal Health Research Center in 1995, continuing in those roles until his recent retirement. He continues to serve as the Associate Director and Professor of the Paul G. Allen School for Global Animal Health at Washington State University. He is a popular scientific speaker and a prolific researcher and writer. He loves his students and has served on dozens of graduate student committees. His One Health oriented research in zoonotic diseases is well recognized. Funded by CDC, he conducted classic studies establishing strategies to prevent zoonotic diseases in Kenya. He has received many awards and extraordinary recognition in his career to include the AAVLD E.P. Pope Award, Washington State University Faculty Member of the Year Award, AVES Diplomate status, and elected to the National Academy of Sciences, Institute of Medicine.
Others awarded an AVES Honorary Diploma for outstanding contributions in epidemiology, public health and One Health with biographical information provided by Dr. Carter included:
Dr. Terri Clark received her DVM from Auburn University. After serving 11 years as a US Army Veterinary Corps Officer, she transferred to the National Institutes of Health as a commissioned corps officer in the US Public Health Service. Currently, she is Director of the Office of Animal Care and Use at the National Institutes of Health. She is Diplomate of the American College of Laboratory Animal Medicine.
Dr. Jason Johnson received a MS in Biomedical Sciences and a DVM degree both from Auburn University. After 7 years in practice, he taught 2 years at the Ross University School of Veterinary Medicine at St. Kitt’s, West Indies. He then joined Lincoln Memorial University as Medical Director of the DeBusk Veterinary Teaching Center, College of Veterinary Medicine. He also served as Executive Director of the Center for Animal Health in Appalachia. Next, he became Associate Dean for Clinical Sciences and in 2016, became Dean of the LMU College of Veterinary Medicine. He is a Diplomate of the American College of Theriogenologists.
Dr. Mo Salman received his BVMS degree from the University of Baghdad, Iraq in 1973, his MPVM B.S. degree in Animal Science in 1976 and his Doctor of Veterinary Medicine both from UC Davis. Currently, he is Professor of Clinical Sciences and Director of the Animal Population Health Institute at Colorado State University. He has received many awards to include Penn Veterinary World Leadership Award. He has had a long and distinguished career in veterinary epidemiology and public health and has authored or coauthored over 300 peer reviewed articles and has served as editor of 7 books. He is a Diplomate of the American College of Veterinary Preventive Medicine and has served as President of that organization. He is also a Fellow of the American College of Epidemiology.
Dr. John Gibbins received his DVM degree from The Ohio State University and a MPH from the Uniformed Services University of Health Sciences in Bethesda, MD. After five years in private practice, he has served in various leadership roles of increasing responsibility in the USAF and CDC to include a stint as an Epidemic Intelligence Officer. He is currently the 11th Chief Veterinary Officer of the United States Public Health Service. He deployed to Liberia in 2014-2015 as part of the Ebola response team. He is a Diplomate of the American College of Veterinary Preventive Medicine.
Dr. Paul Gibbs earned his Bachelor of Veterinary Science (DVM equivalent) and a PhD in Virology from the University of Bristol School of Veterinary Science. He is a member and a Fellow of the Royal College of Veterinary Surgeons. He has worked at the Pirbright Institute as a virology research officer, Professor of Virology and Chief of Microbiology and Parasitology at the University of Florida College of Veterinary Medicine and also served as the Director of the International Center for the University of Florida. He retired in 2012. His professional focus has always been on the control and prevention of emerging animal diseases of viral etiology. He received many honors to include the Pioneer in Virology Award from the AAVLD.
Dr. Thomas Honadel earned his DVM from Kansas State University, a MPVM from the University of California, a Masters in Strategic Studies, and a MS in Reproductive Physiology from Pennsylvania State University. He has had a long career as a United States Army Veterinary Corps officer with leadership roles of increasing responsibility, including three command assignments in overseas locations. He is currently Director, Veterinary Services, Army Public Health Center, Aberdeen proving Ground, MD. He has attained the rank of full Colonel and is a Diplomate of the American College of Veterinary Preventive Medicine.
Dr. Trevor Ames earned his DVM from the Western College of Veterinary Medicine at the University of Saskatchewan, Canada and completed a residency in Large Animal Medicine and a MS at the University of Minnesota. After a stint in practice, he held positions in the Minnesota State Diagnostic Laboratory and later as a Professor of Veterinary Population Medicine with increasing levels of leadership, teaching and research responsibilities. He is currently Dean and Professor, College of Veterinary Medicine, University of Minnesota. He is a Diplomate of the American College of Veterinary Internal Medicine.
Note: "Inaugurated by the American Veterinary Epidemiology Society (AVES) in 1964, the Gold Headed Cane Award was approved as an American Veterinary Medical Association (AVMA) award by the Executive Board in 1996 and is sponsored by Hartz Mountain Corporation, Secaucus, NJ (USA). The award recognizes the achievement of an individual concerned with animal health who has significantly advanced human health through the practice of veterinary epidemiology and public health. Dr. James H. Steele established the award to recognize the outstanding contributions of veterinarian, physician and scientist, Dr. Karl F. Meyer. Originally named the K.F. Meyer Gold Headed Cane Award, it was renamed the K.F. Meyer-James H. Steele Gold Headed Cane Award in 1985 to recognize Dr. Steele for his outstanding contributions to epidemiology and veterinary public health. Today, this award has gained in relevance and stature in concert with AVMA's and many other organizations' endorsement and development of the philosophy of One Health throughout the world."
Craig N. Carter, DVM, PhD, is Director & Professor, Epidemiology of the Veterinary Diagnostic Laboratory, Department of Veterinary Science in the College of Agriculture, Food & the Environment College of Public Health at University of Kentucky in Lexington, KY (USA). Dr. Carter serves as a member of the One Health Initiative team’s Advisory Board http://www.onehealthinitiative.com/advBoard.php.
|The Answer to Cancer Might Be Walking Beside Us - Friday, June 09, 2017
One Health includes Comparative Medicine
…see One Health Umbrella http://www.onehealthinitiative.com/OneHealth2
The Answer to Cancer Might Be Walking Beside Us
Published on May 31, 2017
Colorado State University and Rocky Mountain PBS teamed up to produce a new documentary featuring researchers and clinicians across the country who all have one common goal: One cure for cancer in people and animals.
“…PBS Documentary Heralds Progress, Promise of Comparative Oncology [Cancer]
Perhaps some of the greatest progress to come in the war on cancer will rise from the burgeoning field of comparative oncology, where physicians and veterinarians are battling the disease side-by-side. Some of the remarkable advancements achieved and tantalizing prospects ahead are explored in a compelling half-hour video airing nationally on public television stations this spring and summer. ...”
Note: The program began airing on national public television stations through 42 stations affiliated with the National Educational Telecommunications Association on April 7. The documentary began airing through 33 stations with The Programming Service for Public Television in June.
Editor’s note: This 26:48 minute film is a powerful message to political leaders, the international health care communities and the general public!
|“What’s in a name?” Plenty! - Tuesday, April 21, 2015
A unique historical commentary from a One Health perspective…
“What’s in a name?” Plenty!
Provided to One Health Initiative website www.onehealthinitiative.com April 9, 2015 by:
Jan Clement, MD, Hantavirus Reference Centre, Laboratory of Clinical and Epidemiological Virology & Rega Institute for Medical Research, University of Leuven, U.Z. Gasthuisberg, Herestraat, 49 B-300 Leuven, Belgium (Tel: + 32-16-347908; Fax +32-16-347900; e-mail email@example.com)
John P. Woodall, PhD, Nucleus for the Investigation of Emerging Infectious Diseases, Institute of Medical Biochemistry, Center for Health Sciences, Federal University of Rio de Janeiro, Brazil (e-mail: firstname.lastname@example.org)
Charles H. Calisher, PhD, Arthropod-borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, 3195 Rampart Rd., Foothills Campus, Fort Collins, Colorado, U.S.A. 80523-1690 (e-mail: email@example.com)
“… in 1970, British veterinarians in Uganda sent 699 cattle ticks to the East African Virus Research Institute, from which a strain (AMP 10358) of Congo virus was isolated. These findings suggested that ticks could be vectors of the virus to humans and that livestock might constitute at least hosts if not reservoirs of this newly recognized hemorrhagic fever virus. In May 1973, Greek veterinarians isolated AP 92 virus from ticks feeding on goats in Vergina, northern Greece. Moreover they showed that AP 92 virus clearly reacted in immunodiffusion tests with the same goats’ sera. In the same study they demonstrated that AP 92 virus reacted in the same way with Russian antisera to Crimean hemorrhagic fever virus and with antisera to Congo virus, provided by Chumakov and Casals, respectively. Casals’ paradigm was thereby confirmed. In subsequent years demonstrations of the relatedness of AP 92 and several other Crimean-Congo hemorrhagic fever viruses from Greece and surrounding countries allowed an increasing “One Health approach” to studies of this emerging virus.”
Words are the primary means by which we communicate with each other. Use the wrong word, misuse a pause or a punctuation mark, and you might be misunderstood. Viral taxonomists are particularly fussy about such things. Viral taxonomists have conjured up rules and traditions to follow and most investigators adhere to such rules, which have been published by the International Committee on Taxonomy of Viruses (ICTV; http://www.ictvonline.org/). However, some, by ignorance or arrogance, unintentionally re-invent taxonomy by misnaming their little friends. This has caused complications and confusions that have had to be addressed. The intent of this paper is to present three interesting examples of such misnamings, the problems thereby caused, and the possible solutions to those problems. Reading this One Health Initiative website www.onehealthinitiative.com and/or the One Health Newsletter http://epi.ufl.edu/onehealth/news/one-health-newsletter/ is or should be important to physicians, veterinarians, osteopaths and others in health and environmentally related disciplines who intend to publish or to scan the scientific literature.
Crimean–Congo hemorrhagic fever virus: Although a similar disease had been reported at least 800 years earlier in what is now Tajikistan, beginning in 1944 Russian scientists were first to record the clinical aspects of Crimean hemorrhagic fever (CHF) and in 1947 demonstrated that it had a viral etiology in 200 Russian soldiers appointed by the Russian authorities to harvest crops during wartime in the Crimea instead of the local peasants, who had been driven away. However, due to this unexpected and previously non-scheduled military activity, these soldiers had to sleep outdoors, were fed upon by ticks, and shortly afterwards many suffered a severe hemorrhagic fever, thus named CHF.
In 1945, inoculation of “volunteers” with filtered suspensions of ticks and with tissues of these CHF patients proved that CHF was caused by a tick-transmitted virus (1). However, Russian scientists were unable to isolate the virus. It was not until 1967 that the great Russian virologist Mikhail P. Chumakov and his colleagues formally registered an isolate of the virus from a fatal human case that occurred in Samarkand (in Central Asia, not in the Crimea) in the International Catalogue of Arboviruses Including Certain Other Viruses of Vertebrates (2). This was the result of a visit, prior to publication of the description of Congo virus, to the second author [JPW] of this article who explained that the isolation had been made in newborn mice rather than in the adult mice the Russians had been using. The following year the Russians published additional information about their virus (3), but they did not send the virus to the World Arbovirus Reference Center at Yale University, probably because of political constraints.
However, and unbeknown to them, in 1956 Ghislain Courtois, a physician working at the Provincial Medical Laboratory in Stanleyville (now Kisangani), Belgian Congo (now Democratic Republic of the Congo), had isolated a virus from the blood of a 13 year-old local African male with fever, headache, nausea, vomiting, backache, generalized joint pains, and photophobia. Shortly after this virus isolation in his own laboratory, Courtois himself fell ill for three days with high fever and symptoms similar to his young patient. Courtois isolated a similar virus from his own blood taken on the day of onset of his illness and named it strain V3010. V3010 was later found in Greece, Portugal, South Africa, Madagascar, the Maghreb, Dubai, Saudi Arabia, Kuwait and Iraq. Meanwhile, the virus was re-named “Congo virus”, but descriptive information about it was not published until 1967 (4, 5), the year before Chumakov et al. published their findings. Of note, Congo virus was also isolated from a cow in Kenya (4), and from a goat in Nigeria (6).
In February 1967, Congo virus strain V3010 was sent to the Rockefeller Foundation Virus Laboratory (RFVL) in New York City and there found by Jordi Casals to be identical to another virus, from Uganda, but to no other named virus. Chumakov later sent his strain to the RFVL, where it was found to be identical to the Congo virus (7, 8). In 1970, Chumakov published a book in Russian including a chapter on isolations of the virus from ixodid ticks in European Russia.
Also in 1970, British veterinarians in Uganda sent 699 cattle ticks to the East African Virus Research Institute, from which a strain (AMP 10358) of Congo virus was isolated. These findings suggested that ticks could be vectors of the virus to humans and that livestock might constitute at least hosts if not reservoirs of this newly recognized hemorrhagic fever virus. In May 1973, Greek veterinarians isolated AP 92 virus from ticks feeding on goats in Vergina, northern Greece (9). Moreover they showed that AP 92 virus clearly reacted in immunodiffusion tests with the same goats’ sera. In the same study they demonstrated that AP 92 virus reacted in the same way with Russian antisera to Crimean hemorrhagic fever virus and with antisera to Congo virus, provided by Chumakov and Casals, respectively. Casals’ paradigm was thereby confirmed. In subsequent years demonstrations of the relatedness of AP 92 and several other Crimean-Congo hemorrhagic fever viruses from Greece and surrounding countries allowed an increasing “One Health approach” to studies of this emerging virus (10).
These findings and the dates of their publications created a nomenclatural quandary. Should the virus be named “Congo virus” because it was isolated first, or should it be named “Crimean hemorrhagic fever virus” because a description of the disease was published first and because it incorporated the name of an important human disease? Because this situation had both nomenclatural and political implications, the ICTV attempted to find a proper solution to it. Against the principles of scientific nomenclature based on priority of publication, recognizing that Congo virus was the etiologic agent of illnesses other than relatively simple fevers, including hemorrhagic manifestations (4), and because it seemed too late to rename it “Congo hemorrhagic fever virus”, in 1973 the virus finally was re-named “Crimean-Congo hemorrhagic fever virus” (C-CHFV; family Bunyaviridae, genus Nairovirus). So there are now a number of publications in the literature with “Congo virus” and even “Congo-Crimean hemorrhagic fever virus” in the title. Of course, this did not satisfy everyone but everyone recognized that life and taxonomists are not perfect and further arguments were settled or at least disregarded. The virus is now known to be widespread in Africa, and from the Middle East and southern Europe to Asia, due to the preferred dry and sunny biotope of its global vectors, Hyalomma spp. ticks (10, 11).
Sin Nombre virus: Hantaviruses (family Bunyaviridae, genus Hantavirus), found essentially world-wide, are known to cause hemorrhagic fever with renal involvement in Asia (Hantaan virus) and, albeit somewhat milder disease, in Europe (Puumala virus). Hantaviruses are rodent-borne but, while not seriously affecting the rodent host, cause serious, often life-threatening, illnesses in humans. Prospect Hill hantavirus was recognized in the eastern U.S. but was and is not known to cause human illness. In the spring of 1993 a then unexplained outbreak of adult respiratory distress syndrome was observed in rural residents of the Four Corners region (where New Mexico, Arizona, Utah, and Colorado are contiguous) of the southwestern U.S. Antibody to a recognized hantavirus (Puumala virus) was detected in patient sera, suggesting that whatever the etiologic agent, it likely was a hantavirus (12). It was quickly shown that this disease was caused by a previously unrecognized hantavirus (13).
The virus was first named “Muerto Canyon virus” after a nearby Arizona historic site (Spanish: Canyon del Muerto = Canyon of Death) where, in 1863, the U.S. Army killed Native Americans in order to control the land. That name certainly was unacceptable to Native Americans and to others and so was replaced by “Four Corners virus”. However, the name Four Corners virus was unacceptable to tourist bureaus and others in the area so was discarded and replaced by the name Sin Nombre (Spanish for “without a name”). Viruses traditionally are named for the disease they cause, or the place where they were first recognized (or at least a general location, e.g., “eastern equine encephalitis virus”), so this name was not traditional. However, given the intensity of the epidemiologic and laboratory efforts in the U.S.A. to understand the disease and to prevent it at that time, naming the virus was considered of relatively trivial importance, and the name Sin Nombre virus was accepted by everyone, even if only for expedience.
Tick-borne encephalitis virus: Tick-borne encephalitis is the name of a constellation of clinical findings. It can be caused by any of a number of etiologic agents, including viruses, bacteria, and parasites but is most commonly thought of as being the result of infection with viruses of the family Flaviviridae, genus Flavivirus, although other tick-borne flaviviruses, i.e., Powassan virus, can cause this disease. For many years these viruses were described as distinct and given distinct names in different locations. Later, more detailed studies showed that most were redundant descriptions, the data were merged, and the number of names thankfully reduced. More recently, molecular studies have led to separation of these viruses as subtypes of a single species, Tick-borne encephalitis virus, European subtype, Far Eastern subtype, and Siberian subtype. This nomenclature (and taxonomy) is far from satisfactory, given that species are non-concrete entities (that is, they do not exist, except as names on lists; 14). Obviously (to some), there cannot be a real subtype (a virus) of a non-real entity (a taxon). It is hoped that someday this will be corrected. Meanwhile, the same confusion of species (taxa) and viruses (the real deal) persists, probably and understandably because a relatively few understand what they are talking about.
There are other examples of virus names that are more confusing than helpful. Viruses named after patients; after phages named for the bacteria from which they were isolated (Staphylococcus phage 44AHJD, for example; how does one teach a student to remember that?); names including the name of the genus to which it belongs (Australian bat lyssavirus and bovine viral diarrhea virus 1 (redundant); viral hemorrhagic septicemia virus Fil3 (viral virus?); and many more. Veterinarians almost universally call any of the 26 bluetongue viruses “bluetongue virus” when, in fact, “bluetongue” is the name of a disease and Bluetongue virus is the name of the species (taxon) in which these 26 viruses have been placed. The point to be made is that care should be taken when first naming a virus and inventing a unique abbreviation for it, so that that name and its abbreviation cause the least confusion among those who will be writing and reading about it.
Note: Drs. Jan Clement and Charles Calisher are longstanding One Health Supporters http://www.onehealthinitiative.com/supporters.php. Dr. John (Jack) Woodall is a member of the One Health Initiative team and manager of the OHI website’s ProMED Outbreak Reports page http://www.onehealthinitiative.com/promed.php.
1. Chumakov, M.P. (1947) A new virus disease - Crimean hemorrhagic fever, News of Medicine. Virus Diseases. 44:9-11. (In Russian).
2. Karabatsos, N. (ed) (1985). International Catalogue of Arboviruses Including Certain Other Virus of Vertebrates. 3rd ed., San Antonio, Texas. Am. Soc. Trop. Med. Hyg.
3. Chumakov MP, Butenko AM, Shalunova NV, Mart'ianova LI, Smirnova SE, Bashkirtsev IuN, Zavodova TI, Rubin SG, Tkachenko EA, Karmysheva VIa, Reingol'd VN, Popov GV, and Savinov AP (1968). New data on the viral agent of Crimean hemorrhagic fever. Vopr Virusol. (in Russian) 13:377.
4. Simpson DI, Knight EM, Courtois G, Williams MC, Weinbren MP, Kibukamusoke JW. (1967) Congo virus: a hitherto undescribed virus occurring in Africa. I. Human isolations--clinical notes. East Afr Med J. (1967) 44:86-92.
5. Woodall JP, Williams MC, Simpson DI. (1967) Congo virus: a hitherto undescribed virus occurring in Africa. II. Identification studies. East Afr Med J. 44:93-8.
6, Causey OR, Kemp GE, Madbouly MH, David-West TS. (1970) Congo virus from domestic livestock, African hedgehog, and arthropods in Nigeria. Am J Trop Med Hyg. 19:846-50.
7. Casals J. (1969) Antigenic similarity between the virus causing Crimean hemorrhagic fever and Congo virus. Proc Soc Exp Biol Med. 131:233-6.
8. Chumakov MP, Smirnova SE, Tkachenko EA. (1970) Relationship between strains of Crimean haemorrhagic fever and Congo viruses. Acta Virol. 14:82-5.
9. Papadopoulos O and Koptopoulos G. (1978) Isolation of Crimean-Congo hemorrhagic fever virus from Rhipicephalus bursa ticks in Greece. Acta Microbio Hellenica. 23:20-8 (in Greek with English summary)
10. Papa A, Dalla V, Papadimitriou E, Kartalis GN, Antoniadis A. (2010) Emergence of Crimean-Congo haemorrhagic fever in Greece. Clin Microbiol Infect. 16:843-7.
11. Bente, DA, Forrester NL, Watts DM, McAuley AJ, Whitehouse CA, Bray M (2013) Crimean-Congo hemorrhagic fever: History, epidemiology, pathogenesis, clinical syndrome and genetic diversity. Antiviral Res. 100:159-89.
12. Centers for Disease Control and Prevention: Update: outbreak of hantavirus infection-southwestern United States, 1993. (1993) Morb Mortal Wkly Rep. 42:441-79.
13. Hjelle B, Jenison S, Torrez-Martinez N, Yamada T, Nolte K, Zumwalt R, MacInnes K, Myers G. (1994) A novel hantavirus associated with an outbreak of fatal respiratory disease in the southwestern United States: evolutionary relationships to known hantaviruses. J Virol. 68:592-6.
14. Van Regenmortel MH. (2003) Viruses are real, virus species are man-made, taxonomic constructions. Arch Virol. 148:2481-8.
|Colorado State University (USA) Director of Center for Comparative and Integrative Medicine Issues Strong One Health Endorsement - Wednesday, November 26, 2014
Colorado State University (USA) Director of Center for Comparative and Integrative Medicine Issues Strong One Health Endorsement
“I am delighted that the One Health Initiative is leading the charge of fostering collaboration and communication among all branches of health care. The time has come to make this happen. We need to bridge the gap between humans and animals as well as us and the planet as a matter of not only establishing best medical practices but also ensuring our collective survival.
Every day is “One Health” for me, extending from my human osteopathic medical practice to the Integrative Medicine Service at the Colorado State University Veterinary Teaching Hospital. In my role as Director of the CSU Center for Comparative and Integrative Pain Medicine, I teach, research, and write about scientific, integrative medicine from a One Health perspective. I educate students, practitioners, and the public about ways in which medical acupuncture, botanical medicine, manual therapy, and more apply and translate across the species spectrum (including humans) while at the same time leave a gentler footprint on the planet.”
Provided to the One Health Initiative website November 23, 2014 by:
Narda G. Robinson, DO, DVM, MS, FAAMA
Director, CSU Center for Comparative and Integrative Medicine
Medical Director and Educational Architect, OneHealth SIM
Colorado State University
Veterinary Teaching Hospital
300 West Drake Road
Fort Collins, CO 80523
Editor’s note: Dr. Robinson’s educational background and career http://www.onehealthsim.org/narda-g-robinson-do-dvm-ms-faama/ & http://www.csuvth.colostate.edu/DirectorySearch/Search/MemberProfile/vth/1046 includes a unique combination of human osteopathic medicine (Doctor of Osteopathy degree) http://www.aacom.org/become-a-doctor/about-om#aboutom plus that of being a veterinarian, i.e. trained in veterinary medicine (Doctor of Veterinary Medicine degree) http://en.wikipedia.org/wiki/Veterinary_physician. Obviously this provides an ideal One Medicine/One Health perspective and appreciation for utilizing a multidisciplinary, interdisciplinary and transdisciplinary teaching approach to students at the college of veterinary medicine at Colorado State University (USA) http://csu-cvmbs.colostate.edu/Pages/default.aspx. As a longstanding One Health Supporter/Advocate, Dr. Robinson is also listed on the One Health Initiative website’s Supporters page http://www.onehealthinitiative.com/supporters.php.
“The One Health Initiative http://www.onehealthinitiative.com/ is a movement to forge co-equal, all inclusive collaborations between physicians, osteopaths, veterinarians, dentists, nurses and other scientific-health and environmentally related disciplines, including the American Medical Association, American Veterinary Medical Association, American Academy of Pediatrics, American Nurses Association, American Association of Public Health Physicians, the American Society of Tropical Medicine and Hygiene, the Centers for Disease Control and Prevention (CDC), the United States Department of Agriculture (USDA), and the U.S. National Environmental Health Association (NEHA). …” The One Health concept has gained substantial international recognition during the first two decades of the 21st century, e.g. it is now endorsed by the World Health Health Organization (WHO), Food and Agricultural Organization of the United Nations (FAO), and World Organization of Animal Health (OIE).
|CANCER Investigations for animals and humans…One Health in Action at University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA. (USA) - Saturday, November 02, 2013
CANCER Investigations for animals and humans…One Health in Action at University of Pennsylvania, School of Veterinary Medicine, Philadelphia, PA. (USA)
“…. Founded in 1884, Penn Vet is the only veterinary school developed in association with a medical school. The school is a proud member of the One Health Initiative, linking human, animal, and environmental health.” [See http://www.vet.upenn.edu/about/what-we-do/future-of-veterinary-medicine]
For Immediate Release
November is National Pet Cancer Awareness Month Penn Vet Fights the Nation’s #1 Disease-Related Killer of Dogs and Cats
[November 1, 2013; Philadelphia, PA] – Cancer is the number-one disease-related killer of dogs and cats, claiming millions of pets each year. Through groundbreaking cancer research and a new Comprehensive Cancer Care program, Penn Vet’s Ryan Hospital is dedicated to improving the prevention, diagnosis, and treatment of cancer in animals.
Through a fruitful partnership with Penn Vet’s Veterinary Clinical Investigations Center, Ryan Hospital offers novel therapies that may offer cancer patients – canine and human alike – a viable alternative or complementary treatment to traditional therapies.
In addition, Penn Vet is a member of the Comparative Oncology Trials Consortium, which is run by the National Cancer Institute and provides access to a wide range of new cancer drugs in the early stages of testing.
Some of Penn Vet’s innovative cancer research and clinical offerings are:
It has been 16 months since the first dog diagnosed with spontaneous osteosarcoma received a new bone-cancer vaccine at Penn Vet from Dr. Nicola Mason, the lead investigator on the trial. The vaccine is being administered to dogs diagnosed with osteosarcoma, an aggressive tumor that affects the long bones of large- and giant-breed dogs. Dogs have traveled to Penn Vet from Ohio, Florida, Louisiana, and Montana to receive this novel therapy.
Despite limb amputation and chemotherapy, 60% of dogs with osteosarcoma die within one year of diagnosis. The aim of the vaccine, given to dogs after amputation and chemotherapy, is to prevent metastatic disease and prolong overall survival. Of the first five dogs vaccinated in this clinical trial, four are still alive, having survived between 500 and 590 days, and three dogs are tumor-free. These results suggest that the vaccine stimulates an effective anti-tumor immune response that can kill microscopic metastatic cells and prevent tumor recurrence. Additionally, there have been no long- or short-term complications observed with the vaccine. Given these highly promising results, Penn Vet is collaborating with Colorado State University and the University of Florida on a Phase II clinical trial.
These findings may change the paradigm of canine osteosarcoma treatment and provide essential data to advance this approach in humans, including children with osteosarcoma and adults with a variety of different tumor pathologies, including mammary carcinoma.
The Coriolus versicolor mushroom, known commonly as the Yunzhi mushroom, has been used in traditional Chinese medicine for more than 2,000 years. A compound in the mushroom called polysaccharopeptide, or PSP, is believed to have immune-boosting properties. In the last two decades, some studies have suggested that PSP also has a tumor-fighting effect.
At Penn Vet, Dr. Dottie Brown’s work with I’m-Yunity, a formulation of PSP that has been tested for consistency and good manufacturing processes, resulted in some of the longest survival rates ever reported for dogs with hemangiosarcoma, an aggressive, invasive cancer that arises from the blood cells and typically affects the spleen. Before this study was conducted, the longest reported median survival time of dogs with hemangiosarcoma of the spleen that did not undergo further treatment was 86 days. Dogs enrolled in Penn Vet’s trial lived beyond a year with nothing other than the mushroom compound as treatment.
Penn Vet researchers are currently pursuing further trials to confirm and refine these results. One trial will compare I’m-Yunity to a placebo for owners who opt not to pursue chemotherapy in their pet, and another will compare the compound to standard-of-care chemotherapy. Depending on those results, veterinarians could eventually prescribe the compound for treating hemangiosarcoma, and perhaps other cancers, in dogs. The company that manufacturers I’m-Yunity may also pursue large-scale clinical trials in humans.
Shelter Canine Mammary Tumor Program
The goal of the Penn Vet Shelter Canine Mammary Tumor Program is to advance knowledge of breast cancer in both dogs and humans. Led by Dr. Karin Sorenmo, the program provides care to shelter dogs with mammary tumors that are homeless and without access to the care they need to survive. Penn Vet covers surgery and follow-up care costs and helps facilitate adoption.
Mammary tumors in dogs and breast cancer in women have many similarities, both in terms of risk factors and biology. Shelter dogs provide an ideal population for studying mammary tumors because only 10 percent of animals received into shelters have been spayed or neutered. The incidence of mammary tumors in unspayed female dogs is at least four times greater than in spayed dogs. In addition, many of the dogs have multiple tumors, often in different stages of malignant transformation, and therefore provide a unique opportunity to study cancer progression.
Cancer Imaging Systems
Penn Vet’s Dr. David Holt has partnered with Penn Medicine to improve detection of surgical margins at the time of surgery to remove soft tissue sarcomas. Dr. Holt currently offers a surgery using dye and special imaging equipment to Ryan Hospital patients. This technique is vital in both veterinary and human surgical oncology to ensure that the entire tumor is resected.
Comprehensive Cancer Care
Penn Vet’s Ryan Hospital is changing the face of cancer medicine with a Comprehensive Cancer Care program – a multidisciplinary approach to evaluate and treat cancer patients. Through this program, board-certified specialists in medical, surgical, and radiation oncology collaborate to provide a comprehensive assessment of each patient’s cancer care needs, resulting in better care, more efficient service, and a more complete approach. Ryan Hospital is one of only three veterinary comprehensive cancer care centers in the nation.
Ryan Hospital clients have access to some of the finest medical and radiation oncologists; a top-notch surgery team, including one of the only fellowship-trained surgical oncologists in the area; an interventional radiology specialist; a world-class dentistry and oral surgery team, distinguished by their training in maxillofacial cancer surgery; board-certified nutrition specialists who offer consultations on diet and feeding strategies that may improve quality of life or treatment outcomes; a grief counselor and support group aimed at helping those caring for chronically ill, terminally ill, or aging pets; and some of the most modern facilities and equipment in veterinary medicine – all in one building. To make an appointment, call 215-746-8387.
About Penn Vet
Penn Vet is a global leader in veterinary medicine education, research, and clinical care. Founded in 1884, Penn Vet is the only veterinary school developed in association with a medical school. The school is a proud member of the One Health Initiative, linking human, animal, and environmental health. [See http://www.vet.upenn.edu/about/what-we-do/future-of-veterinary-medicine]
Penn Vet serves a diverse population of animals at its two campuses, which include extensive diagnostic and research laboratories. Ryan Hospital in Philadelphia provides care for dogs, cats, and other domestic/companion animals, seeing nearly 33,000 patients a year. New Bolton Center, Penn Vet’s large-animal hospital on nearly 700 acres in rural Kennett Square, PA, cares for horses and livestock/farm animals, treating 33,000 patients each year – 4,100 in the hospital and 29,000 at farms through the Field Service. In addition, New Bolton Center’s campus includes a swine center, working dairy, and poultry unit that provide valuable research for the agriculture industry.
For more information, visit www.vet.upenn.edu.
Director of Communications
University of Pennsylvania
School of Veterinary Medicine
3800 Spruce Street
Philadelphia, PA 19104 (USA)
Ashley Berke, Director of Communications, firstname.lastname@example.org
John Donges, Communications Coordinator, email@example.com
|One Health Initiative website team’s Honorary Advisory Board Joined by New Member - Wednesday, February 29, 2012
One Health Initiative website team’s Honorary Advisory Board Joined by New Member
February 29, 2012—The One Health Initiative honorary Advisory Board was established on December 1, 2010.
Today, we are pleased to announce that among the current outstanding One Health supporters/advocates and recognized leaders, Indu Mani, DVM, DSc, editor of Clinician’s Brief http://www.cliniciansbrief.com/, the official small animal veterinary medical journal of the North American Veterinary Conference (NAVC), has graciously agreed to serve as a participant member. Dr. Mani, earned her Doctor of Veterinary Medicine degree from the College of Veterinary Medicine at Colorado State University and a Doctor of Science degree from Harvard School of Public Health in Boston, MA (USA) with emphasis on immunology and infectious diseases. She also practices small animal veterinary medicine & surgery.
Dr. Mani’s unique professional qualifications, having both private practice and public health backgrounds, led her to help establish Clinician’s Brief as what is believed to be the first peer reviewed small animal medicine/surgery journal in the world with a visionary “One Health” oriented section viz. Capsules.
The updated list of 25 distinguished members posted is now http://www.onehealthinitiative.com/advBoard.php:
Larry R. Anderson, DVM, MD - Sumner County Family Care Center, PA, Wellington, Kansas (USA)
Steven W. Atwood, VMD, MRCVS, MD, MPH – Animal Health Care Associates, West Tisbury, MA (USA)
B. Sonny Bal, MD, JD, MBA - Associate Professor, Department of Orthopaedic Surgery, University of Missouri School of Medicine (USA)
Donald S. Burke, MD - Dean, Graduate School of Public Health, University of Pittsburgh (USA)
Carina Blackmore, DVM, PhD – State Public Health Veterinarian, Florida Department of Health (USA)
Craig N. Carter, DVM, PhD – Director, University of Kentucky, Veterinary Diagnostic Laboratory (USA)
Nancy Chaney, RN, BA, MS – Mayor City of Moscow, Idaho, President of the Association of Idaho Cities, Board member of the Directors of the National League of Cities (USA)
Lisa A. Conti, DVM, MPH – Former Director, Florida Department of Health, Environmental Health Division (USA)
James L. Cook, DVM, PhD, Diplomate ACVS - William & Kathryn Allen Distinguished Professor in Orthopaedic Surgery, Director, Comparative Orthopaedic Laboratory, University of Missouri (USA)
Mary Echols, DVM, MPH – Editor, One Health Newsletter and Public Health Veterinarian, Palm Beach County (FL) Health Department (USA)
David N. Fisman, MD, MPH – Dalla Lana School of Public Health, University of Toronto and Department of Medicine, North York General Hospital (Canada).
James G. Fox, DVM, MS, DACLAM, FIDSA - Professor and Director of the Division of Comparative Medicine and Professor in the Department of Biological Engineering, Massachusetts Institute of Technology (USA)
Greg Gray, MD, MPH, FIDSA - Professor and Chair, Department of Environmental and Global Health, College of Public Health and Health Professions; Professor, Department of Infectious Diseases and Pathology, College of Veterinary Medicine; and Director, Global Pathogens Laboratory, University of Florida (USA)
David L. Heymann, MD – Editor, Control of Communicable Diseases Manual and Director, U.K. Health Protection Agency (United Kingdom)
James M. Hughes, MD - Professor of Medicine and Public Health, Emory University (USA)
Martyn H. Jeggo, BVetMed, PhD – Director, CSIRO Livestock Industries Australian Animal Health Laboratory (Australia)
Lawrence C. Madoff, MD - Editor, ProMED-mail, Associate Professor of Medicine, Harvard Medical School and Associate Physician, Brigham and Women’s Hospital (USA)
Indu Mani, DVM, DSc - Editor, Clinician’s Brief, the North American Veterinary Conference’s (NAVC) official small animal veterinary medical journal (USA)
Björn Olsen, MD - Professor, Senior Physician Infectious Diseases Uppsala University and University Hospital (Sweden)
Michael T. Osterholm, PhD, MPH – Director, Center for Infectious Disease Research & Policy (CIDRAP) Academic Health Center—University of Minnesota (USA)
Peter M. Rabinowitz, MD, MPH – Associate Professor of Medicine, Yale School of Medicine, Director of Yale Human Animal Medicine Project, Yale Occupational and Environmental Medicine Program (USA)
Ralph C. Richardson, DVM, Diplomate ACVIM (Oncology, Internal Med) – Dean, College of Veterinary Medicine, Kansas State University (USA)
Kevin M. Sherin, MD, MPH, FACPM, FAAFP - Director, Orange County (Florida) Health Department (USA)
Gary Simpson, PhD, MD, MSc, MPH – College Master-Paul L. Foster School of Medicine - Texas Tech University Health Science Center, Professor of Infectious Diseases in Medical Education (USA)
James H. Steele, DVM, MPH – Professor Emeritus, University of Texas School of Public Health (USA)
|1st International Biosafety and Biocontainment Symposium - February 6-9, 2011 - Tuesday, January 04, 2011
1st International Biosafety and Biocontainment Symposium - February 6-9, 2011
1st International Biosafety & Biocontainment Symposium
United States Department of Agriculture (USDA) – Animal Research Service (ARS)
Animal Production & Protection: Challenges, Risks, and Best Practices
Baltimore Marriott Inner Harbor at Camden Yards
Baltimore, Maryland (USA)
Featured keynote speakers: Jerry Jaax, DVM, "Agricultural Infrastructure Challenges,"and Laura H. Kahn, MD, MPH, MPP, "One Health"
Choose from six different preconference courses offered on Sunday
Two and a half days: Expert speakers will be presenting topics on animal livestock, aquaculture, and wildlife health issues associated with agricultural research, diagnostics, and response
Exhibits showcasing the latest agricultural biosafety products and services
Invaluable networking with professionals from the biosafety and scientific research industries, organizations, and agencies
As an IACET Authorized Provider, ABSA offers CEUs for these programs that qualify under IACET guidelines.
USDA ARS is partnering with the American Biological Safety Association (ABSA) who will be managing the symposium. The focus of this first symposium will be on animal (livestock, aquaculture, and wildlife) health issues associated with agricultural research, diagnostics, and response.
For more information, please contact Ed Stygar at firstname.lastname@example.org
Wednesday, February 9, 2011
7:00 am - 1:00 pm Registration
8:00 - 12:00 pm
Session VI: One Health
Moderator: Lonnie King, DVM, MS, MPA Ohio State University, Columbus, OH
8:00 - 8:50 am Keynote–One Health – Laura H. Kahn, MD, MPH, MPP, Princeton University, Princeton, New Jersey
8:50 - 9:20 am #20 - NBAF Project Update - Michelle Colby, DVM, Department of Homeland Security, Washington, DC
9:20 - 9:50 am #21 - Applications of One Health - Mo Salman, DVM, PhD, DACVPM, Colorado State University, Fort Collins, CO
9:50 - 10:20 am #22 - Laboratory Twinning - Kate Glynn, DVM, World Health Organization, Paris, France
10:20 - 10:35 am Break
10:35 - 11:05 am #23 - Use of Forensics Laboratories in Outbreaks - Robert Bull, PhD, FBI Laboratory, Quantico, VA
11:05 - 12:30 pm Session VI Roundtable–One Health Realities & Solutions
Moderator: Lonnie King, DVM, MS, MPA, Ohio State University, Columbus, OH
Panelists: Laura H. Kahn, MD, MPH, MPP, Princeton University, Princeton, N.J.; Beth Lautner, DVM, United States Department of Agriculture, Animal and Plant Health Inspection Service, Ames, IA; Mo Salman, DVM, PhD, DACVPM, Colorado State University, Fort Collins, CO; Kate Glynn, DVM, World Health Organization, Paris, France
12:30 pm Closing Comments & Adjourn - Joe Kozlovac, MS, RBP, CBSP, United States Department of Agriculture, Agricultural Research Services, Beltsville, MD