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Editorial: 'ONE HEALTH' and Parasitology - Tuesday, August 25, 2009

“ONE HEALTH” Editorial Published on ‘Parasites and Vectors’ ...

'One Health' and Parasitology

 

http://www.parasitesandvectors.com/

 

Please see http://www.parasitesandvectors.com/content/2/1/36

or PDF at http://www.parasitesandvectors.com/content/pdf/1756-3305-2-36.pdf

Editorial    
'ONE HEALTH' and parasitology
Bruce Kaplan, Laura H Kahn, Thomas P Monath, Jack Woodall
Parasites & Vectors 2009, 2:36 (12 August 2009)
[Abstract] [Full Text] [PDF] [PubMed] [Related articles]


HISTORIC “One Health” Monograph Published - Friday, June 26, 2009

HISTORIC “One Health” Monograph Published

 

Veterinaria Italiana

 

http://www.izs.it/vet_italiana/2009/45_1/45_1.htm

 

 ‘One Health – One Medicine’:

 

linking human, animal and environmental health

 

Volume 45 (1) / January – March 2009

 

Bruce Kaplan, DVM, Laura H. Kahn, MD, MPH, MPP and Thomas P. Monath, MD, Editors

 

This monograph contains a variety of 13 scientific One Health essays by 53 authors & co-authors from 12 countries including the U.S.  These provide further justification for invoking a rapid One Health paradigm shift for the benefit of human and animal health and health care locally, nationally and globally.

 

“It is a glorious feeling to discover the unity of a set of phenomena that seem at first to be completely separate”

 

Albert Einstein, April 14, 1901

 

 

‘One Health - One Medicine’: linking human, animal and environmental health


Bruce Kaplan, DVM, Laura H. Kahn, MD, MPH, MPP & Thomas P. Monath, MD

The brewing storm  http://www.izs.it/vet_italiana/2009/45_1/9.htm                                                              9-18

 

 

 

Laura H. Kahn, MD, MPH, MPP

‘One Medicine - One Health’ interview with Ronald M. Davis†, MD, President of the American Medical Association,  http://www.izs.it/vet_italiana/2009/45_1/19.htm                                      19-21

 

Peter Rabinowitz, MD, MPH, Matthew Scotch, PhD, MPH & Lisa Conti, DVM, MPH

Human and animal sentinels for shared health risks             23-34

 

E. Paul J. Gibbs, BVSc, PhD, FRCVS & Tara C. Anderson, DVM, MPH

‘One World - One Health’ and the global challenge of epidemic diseases of viral aetiology                                                                        35-44

 

 

 

Eyal Klement, DVM, MSc, Nahum Shpigel, DVM, PhD, Ran D. Balicer, MD, MPH, Gad Baneth, DVM, PhD, Itamar Grotto, MD, MPH & Nadav Davidovitch, MD, MPH, PhD

One Health’, from science to policy: examples from the Israeli experience          45-53

 

Alemka Markotiæ, MD, PhD, Lidija Cvetko Krajinoviæ, BSc, Josip Margaletiæ, PhD, Nenad Turk, DVM, PhD, Marica Miletiæ-Medved, MD, PhD, Ljiljana ˇmak, MD, PhD, Mateja Jankoviæ, MD, Ivan-Christian Kurolt, BSc, Silvija Šoprek, MD, Oktavija Ðakoviæ Rode, MD, MSc, Zoran Milas, DVM, PhD, Ivan Puljiz, MD, PhD, Dragan Ledina, MD, MSc, Mirsada Hukiæ, MD, PhD & Ilija Kuzman, MD, PhD

Zoonoses and vector-borne diseases in Croatia - a multidisciplinary approach  55-66

 

Stephen J. Prowse, PhD, Nigel Perkins, BVSc (Hon), MS, PhD & Hume Field, BVSc, MSc, PhD

Strategies for enhancing Australias capacity to respond to emerging

infectious diseases                                                                                   67-78

 

Jacqueline Fletcher, PhD, David Franz, DVM, PhD & J. Eugene LeClerc, PhD

Healthy plants: necessary for a balanced One Health concept      79-95

 

Val Beasley, DVM, PhD

One Toxicology, Ecosystem Health and One Health                      97-110

 

Douglas Thamm, VMD & Steven Dow, DVM, PhD

How companion animals contribute to the fight against cancer in humans   111-120

 

Jakob Zinsstag, DVM, PhD, Esther Schelling, DVM, PhD, Bassirou Bonfoh, DVM, PhD, Anthony R. Fooks, PhD, CBiol, FiBiol, Joldoshbek Kasymbekov, DVM, PhD, David Waltner-Toews, DVM, PhD & Marcel Tanner, PhD, MPH

Towards a ‘One Health’ research and application tool box                   121-133

 

Charles O. Thoen, DVM, PhD, Philip A. LoBue, MD, Donald A. Enarson, MD, John B. Kaneene, DVM, MPH, PhD & Isabel N. de Kantor, PhD

Tuberculosis: a re-emerging disease in animals and humans              135-181

 

Joan Hendricks, VMD, PhD, Charles D. Newton, DVM, MS & Arthur Rubenstein, MBBCh (MD)

One Medicine - One Health at the School of Veterinary Medicine of the University of Pennsylvania - the first 125 years                                       183-194

 

Laura H. Kahn, MD, MPH, MPP, Bruce Kaplan, DVM & Thomas P. Monath, MD

One Health’ in Action Series: Nos 1-8  

 

In memoriam

 

Great 21st century physician One Health leader dies    Ronald M. Davis, MD
Past President, American Medical Association     209

 

195-208

 

 

 

   

 

 

 

 

 

 

 

     

 

 


Orthopedic Surgeons (a veterinarian and physician) Research Creative Hip and Knee Replacements for Dogs and Humans Together - Wednesday, June 03, 2009

One Health in ACTION! 

Orthopedic Surgeons (a veterinarian and physician) Research Creative Hip and Knee Replacements for Dogs and Humans Together

Veterinarian James "Jimi" Cook, DVM, PhD, a University of Missouri- Columbia college of veterinary medicine professor of orthopedic surgery and physician B. Sonny Bal, MD, JD, MBA, Associate Professor of Orthopedic Surgery college of medicine have collaborated for over seven years on efforts to create hip and knee replacements without using commonplace biomechanical metal and plastic materials.  The technique being developed by Dr. Cook for dogs initially, involves use of laboratory grown tissue (cartilage) that can be molded into replicas of joints that require replacement.  Drs. Bal and Cook are concomitantly developing a process whereby a similar process can be adapted for humans.  

The two One Health supporters were recognized for their important biomedical research in the MISSOURIAN Newspaper, Tuesday, June 2, 2009.  This is another significant example of why “One Health” needs to be implemented into the scheme of health and health care as a paradigm shift.  Humans and animals will obviously benefit immensely in fields of biomedical research and public health.

http://www.columbiamissourian.com/stories/2009/06/02/mu-research-may-lead-treatment-lou-gehrigs-disease/

“Jimi Cook [DVM, PhD] and I have worked alongside a team of specialists from medicine, veterinary medicine, and engineering for seven years now. Our current focus is to develop replacement joints that mimic the natural process of cartilage and bone formation as they grow and develop. This kind of collaboration is essential to the creation of better options for the replacement of failing hips and other joints. By working with specialists in the veterinary field, we are able to evaluate our technology more rapidly, and that means that we will be able to develop these alternatives for humans sooner than if we worked alone.”

 

Sonny Bal [MD, JD, MBA]

 

 MU builds ties between veterinary and human researchers

Tuesday, June 2, 2009 | 12:01 a.m. CDT

(Permission to publish granted June 3, 2009)

 

*Please visit website link above to see accompanying Photo of Drs. Cook and Bal along with descriptive caption. You may also view the complete article with photo and caption on this website's Publication page.

 

BY Tim Lloyd

COLUMBIA — Jimi Cook’s grandfather was one of the first patients in the U.S. to have artificial knee replacement surgery. 

“From the time I was 8 years old, I have always wanted to find a better way to treat arthritis after watching him go through six knee replacements,” Cook said. He is an associate professor of small animal surgery and director of the Comparative Orthopaedic Laboratory at the MU School of Veterinary Medicine. 

Nearly three decades after his grandfather's surgeries, Cook is developing new technology that might make repeat surgeries things of the past. But his discovery didn’t only come from studying the human skeletal system.

“Dogs are the closest replicas of humans for us when it comes to studying clinical problems in knees and hips,” he said.

Cook's new technique involves growing cartilage in a lab that can be molded into permanent joint replacements. It’s just one in a growing number of human medical advancements made by researchers studying their canine companions.

Growing knees, hips and shoulders

In the sterile petri dishes of a walk-in-closet sized lab, cells divide and multiply into living cartilage that Cook plans to mold into new knees and hips for dogs.    

“The goal is to make replacement parts,” said Sonny Bal, an associate professor of orthopedic surgery at the MU School of Medicine. Bal is working with Cook on the human application of his technique.  

The collaboration between Cook and Bal is welcome news to Bob Reeves, a retired Columbia resident who in the last four years has had both of his knees replaced with metal transplants. The surgeries are the most recent in a series of medical procedures that are likely the result of injuries he suffered in a construction accident almost 50 years ago, Reeves said.  

“I was working to pay my way through college when a scaffold broke and I fell 35 feet,” Reeves said. “I’m sort of like 'The Six Million Dollar Man,' but my wife says I’m more like $49.95.”

Reeves said that even though he has worked hard to regain strength and motion in his body, the metal replacement parts have limited the improvements.

“My body has healed around the metal parts, but metal won’t improve with the rest of my body,” Reeves said. 

Cook’s technique replaces damaged joints with living tissue, meaning patients like Reeves could get a new set of knees that would heal with the rest of their bodies. 

“That would be extremely helpful for people who need transplants,” said Robert Kimble, a 78-year-old who has had three knee transplants in the last eight years. “That would be a heck of an improvement.”

The technique being developed by Cook mimics the natural process of cartilage and bone formation during growth and development of the joints. Molds of joints are then made and filled with lab-grown cartilage, forming exact replicas of joints in need of replacement.  

Because conditions like arthritis progress month to years faster in dogs, Cook is able to more rapidly test the effectiveness of his technique.  

“In dogs with arthritis, everything happens much faster,” Cook said. “This allows us to see the results of our research sooner than if we were working on humans.”

The Food and Drug Administration recognizes physical similarities between dogs and humans, and if a new treatment is proved effective for dogs, it can more quickly be tested in humans. 

“We’ve been working on this for seven years,” Cook said. “It would have taken 15 to 20 years if we were working on humans.”

This summer, Cook will begin testing his technology on dogs in need of new hip joints. If effective, the tests will continue into long-term studies. Human testing is the final phase.

New horizons

Cook and Bal are widening the scope of previous collaborations to include engineers from the Missouri University of Science and Technology and researchers at Columbia University in New York City.

The multidisciplinary approach puts MU in line with a worldwide effort to strengthen ties between veterinary medical and human medical research, said Bruce Kaplan, a Florida veterinarian and co-founder of the Web site Onehealthinitiative.com.

The site promotes the One Health movement, which advocates collaboration between veterinary and human research. The concept has received endorsements from the American Medical Association and the American Veterinary Medical Association.

“The campuses that have veterinarians and physicians working together are where a good deal of biomedical research is done,” Kaplan said. “Dr. Cook has become a giant in the field.”

Recently discovered neurological similarities between dogs and humans could lead to treatments for degenerative brain diseases.

Veterinary neurologist Joan Coates is part of a research team that found a genetic link between hereditary degenerative myelopathy (DM) in dogs and amyotrophic lateral sclerosis (ALS), commonly referred to as Lou Gehrig’s Disease.

“There is a potential that this discovery may assist with finding new treatments that will slow the progress of some forms of hereditary ALS,” Coates said. 

She is quick to point out that years of study are needed before a treatment for humans can be developed.

“We still have a lot of work to develop markers of disease in dogs in order to evaluate disease progression and response to potential treatments,” Coates said.

Working with dogs could shorten the time frame.

“ALS takes two to five years to progress in humans; it takes six months to a year in dogs,” Coates said. “We may be able to test and see more results more quickly when evaluating potential therapies in dogs.”

Kaplan said Cook and Coates' advances could just be the beginning of new advances in the field of veterinary and human medicine. 

“If you combine the brains and minds of different medicines, you will come up with things that would have not come about otherwise,” Kaplan said. “It could be miraculous.” 


 
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